동식물위생연구 국제공인연구실 WOAH reference lab 브루셀라병연구실
동식물위생연구에 대한 모든 정보가 있습니다.
WOAH 77차 총회에서 아·태 지역 최초로 브루셀라병 표준실험실로 인정받음(2009년 5월)
이진주 수의연구사
[농림축산검역본부]
실험실-세균질병과
[농림축산검역본부]
Molecular epidemiological investigation of Brucella melitensis circulating in Mongolia by MLVA16(2018-01-05) | |||||
---|---|---|---|---|---|
담당부서 | 동식물위생연구부 | 작성자 | 이진주 | 0 | 2018-01-05 |
Molecular epidemiological investigation of Brucella melitensis circulating in Mongolia by MLVA16 Comp Immunol Microbiol Infect Dis. 78(4): 557–562. Kang SI, Her M, Erdenebaataar J, Vanaabaatar B, Cho HR, Sung SR, Lee JJ, Jung SC, Park YH, Kim JY ABSTRACT Mongolia has a high incidence of brucellosis in human and animals due to livestock husbandry. To investigate the genetic characteristics of Mongolian B. melitensis, an MLVA (multi-locus variable-number tandem-repeat analysis)-16 assay was performed with 94 B. melitensis isolates. They were identified as B. melitensis biovar (bv.) 1 (67), 3 (10) and Rev. 1 vaccine strains (17) using a classical biotyping and multiplex PCR. In genotyping, three human isolates were grouped at 2 genotypes with sheep isolates, and it implies that B. melitensis are cross-infected between human and livestock. In the parsimony analysis, Mongolian B. melitensis isolates had high genetic similarity with Chinese strains, likely due to the geographical proximity, clustered distinctively as compared with other foreign isolates. B. melitensis Rev. 1 vaccine strains were divided into 4 genotypes with 92% similarity. In the analysis of Rev.1 strains, the risk of mutation of vaccine strain might not be overlooked. Animal quarantines should be strengthened to prevent the spread of Brucella species among adjacent countries.
|
|||||
첨부파일 | 1개 / 1463KB (전체저장 버튼 클릭 시 압축파일로 저장됩니다.)
|
||||