Designated as WOAH Reference Laboratory for Brucellosis at 77th WOAH general session in May, 2009.
Dr. Jin-Ju Lee
[Animal and Plant Quarantine Agency]
Bacterial Disease Division
[Animal and Plant Quarantine Agency]
A Genetic Comparison of Brucella abortus Isolates from Animals and Humans by Using a MLVA Assay(2012-01-10) | |||||
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Part | Animal and Plant Health Research | Charger | Moon Her | date | 2012-01-10 |
Her M*, Kang SI, Kim JW, Kim JY, Hwang IY, Jung SC, Park SH, Park MY, Yoo H. 2010. A Genetic Comparison of Brucella abortus Isolates from Animals and Humans by Using a MLVA Assay. J Microbiol Biotechnol. 20(12):1750-1755. Abstract The MLVA assay is known to have a high ability to identify and discriminate Brucella species, so that it can be used as an epidemiological tool to discriminate Brucella isolates originating from restricted geographic sources. In this study, the genetic profiles of 38 B. abortus isolates from humans were analyzed and compared with genotypes from animal isolates in South Korea. As a result, it was found that they did not show high genetic diversity and were compacted. They were clustered together with animal isolates, showing a significant correlation to regional distributions. With its ability to prove a significant genetic correlation among B. abortus isolates from animals and humans in South Korea, the MLVA assay could be utilized as part of a program to control and eradicate brucellosis, one of the major zoonoses. This study represents the first data of genetic correlation of B. abortus isolates from humans and animals in South Korea. |
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